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Microbiome Analyses

Clinical production phase sequencing data is currently being processed into NCBI's dbGap database. Once sequence is available, the HMP will begin analyses including, but not limited to:

  • Phylogenetic Analysis of 16S rRNA sequence using RDB classifier
  • Taxonomic binning of metagenomic wgs sequence
  • Read-based community comparisons of metagenomic wgs sequence
  • Functional annotation of the human microbiome, and identification of gene classes of particular interest
  • Identification of metabolic pathways
  • Comparisons of microbiomes from different body sites/subjects on multiple levels: organisms, genes, pathways