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Clinical Sampling

Initial 16S and metagenomic wgs sequencing is being performed on samples collected from ~250 healthy adult men and women between the ages of 18 and 40, recruited at Baylor College of Medicine in Houston, TX and Washington University in St. Louis, MO. Samples are collected in a non-invasive manner from five body sites: oral cavity, skin, nasal cavity, gastrointestinal tract and vagina. In addition, subjects will donate blood to be used to examine the relationship of host genotype to an individual's microbiota, and serum for possible future studies, such as determination of immune response to organisms identified in the individual's microbiome.

See the HMP Core Microbiome Sampling Protocol for more information and descriptions of sampling procedures to be used for collecting reference metagenomic samples under the HMP.

Study Participant information

These documents represent the consent forms being used at Washington University and Baylor College of Medicine, along with supplemental information being provided to potential donors.


Study participants who have questions or concerns about any aspect of the project should contact:

Baylor College of Medicine


James Versalovic, MD, PhD

Baylor College of Medicine

Texas Children's Hospital

6621 Fannin Street, MC 1-2261

Houston, TX 77030

phone: (832) 824-2213

email: jamesv@bcm.edu

Wendy Keitel, MD

Department of Molecular Virology and Microbiology

Baylor College of Medicine 280

One Baylor Plaza

Houston, TX 77030

phone: (713) 798-5250

email: wkeitel@bcm.edu

Washington University


Mark Watson, MD, PhD

Washington University School of Medicine

Campus Box 8118

660 S. Euclid Avenue

St. Louis, MO 63110

phone: (314) 454-7919

email: watsonm@wustl.edu

Michael Dunne, PhD

Washington University School of Medicine

258A Barnes-Jewish Hospital Service Building

St. Louis, MO 63110

phone: (314) 362-1547

email: dunne@wustl.edu