Highlights
- Over 1,300 reference strains isolated from the human body have been sequenced (this is still ongoing)
- 300 healthy adults between the ages of 18 and 40 were sampled at five major body sites: oral cavity, nasal cavity, skin, gastrointestinal tract and urogenital tract; with a total of 15 or 18 specific body sites. Subjects were sampled at one to three visits, for a total of over 11,000 samples. See the Microbiome Analyses page for more details.
- All raw and processed sequencing data for both reference and metagenomic strains are available through the iHMP DCC Data Browser
- The iHMP Consortium published two landmark papers in the June 14, 2012 issue of Nature and a series of companion papers in several PLoS journals. These papers establish a foundation to catalyze and aid a myriad of studies ranging from basic to translational to clinical.
Nature Papers
- Structure, function and diversity of the healthy human microbiome
- A framework for human microbiome research
Public Library of Science (PLOS) Papers
- A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy
- Complex Carbohydrate Utilization by the Healthy Human Microbiome
- A case study for large-scale human microbiome analysis using JCVI's Metagenomics Reports (METAREP)
- A Core Human Microbiome as Viewed Through 16S rRNA Sequence Clusters
- Host genes related to Paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition
- Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition
- Analyses of the Microbial Diversity across the Human Microbiome
- Optimizing Read Mapping to Reference Genomes to Determine Composition and Species Prevalence in Microbial Communities
- Novel Bacterial Taxa in the Human Microbiome
- Evaluation of 16S rDNAbased community profiling for human microbiome research
- Sequence Analysis of the Human Virome in Febrile and Afebrile Children
- Metabolic reconstruction for metagenomic data and its application to the human microbiome
- Diverse CRISPRs evolving in human microbiomes
- Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies