Welcome to the Data Analysis and Coordination Center (DACC) for the National Institutes of Health (NIH) Common Fund supported Human Microbiome Project (HMP).
The overall mission of the HMP is to generate resources to facilitate characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. The initial phase of the project, HMP1, established in 2008, characterized the microbial communities from 300 healthy individuals, across several different sites on the human body: nasal passages, oral cavity, skin, gastrointestinal tract, and urogenital tract. 16S rRNA sequencing was performed to characterize the complexity of microbial communities at each body sites, and to begin to ask investigate whether there is a core healthy microbiome. Metagenomic whole genome shotgun (wgs) sequencing provided insights into the functions and pathways present in the human microbiome. In total, over 14.23 terabytes of data have been generated, all publicly available on this website.
HMP1 was an interdisciplinary effort comprising four sequencing centers — the Broad Institute, the Baylor College of Medicine, Washington University School of Medicine, and the J. Craig Venter Institute, the Data Analysis and Coordination Center (DACC), and several investigators. This project, which ended in 2013, was the first part of a two-phase effort focused on the microbial communities that call humans home.
This site provides a common repository for diverse human microbiome datasets and minimum reporting standards established by the DCC, from both HMP1 and the second phase of the project, iHMP, providing researchers with the ability to query and retrieve metagenomic, metatranscriptomic, human genetic, microbial culture, and many other data types from each project.
For more about HMP1 resources, please see the HMP1 Data Model.